4cl1: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 ==The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors==
-<StructureSection load='4cl1' size='340' side='right' caption='[[4cl1]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
+<StructureSection load='4cl1' size='340' side='right'caption='[[4cl1]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4cl1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_(isolate_h77) Hepatitis c virus (isolate h77)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CL1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CL1 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4cl1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_C_virus_(isolate_H77) Hepatitis C virus (isolate H77)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CL1 FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cl1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cl1 RCSB], [http://www.ebi.ac.uk/pdbsum/4cl1 PDBsum]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-<table>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cl1 OCA], [https://pdbe.org/4cl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cl1 RCSB], [https://www.ebi.ac.uk/pdbsum/4cl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cl1 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/K4KA16_9HEPC K4KA16_9HEPC]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 12: / Line 16: @@
 The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors.,Lambert SM, Langley DR, Garnett JA, Angell R, Hedgethorne K, Meanwell NA, Matthews SJ Protein Sci. 2014 Mar 18. doi: 10.1002/pro.2456. PMID:24639329<ref>PMID:24639329</ref>
-From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 4cl1" style="background-color:#fffaf0;"></div>
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Angell, R.]]
+[[Category: Large Structures]]
-[[Category: Garnett, J A.]]
+[[Category: Angell R]]
-[[Category: Hedgethorne, K.]]
+[[Category: Garnett JA]]
-[[Category: Lambert, S M.]]
+[[Category: Hedgethorne K]]
-[[Category: Langley, D R.]]
+[[Category: Lambert SM]]
-[[Category: Matthews, S J.]]
+[[Category: Langley DR]]
-[[Category: Meanwell, N A.]]
+[[Category: Matthews SJ]]
-[[Category: Viral protein]]
+[[Category: Meanwell NA]]