4c7o: Difference between revisions

<StructureSection load='4c7o' size='340' side='right'caption='[[4c7o]], [[Resolution|resolution]] 2.60&Aring;' scene=''>

<table><tr><td colspan='2'>[[4c7o]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C7O FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c7o OCA], [https://pdbe.org/4c7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c7o RCSB], [https://www.ebi.ac.uk/pdbsum/4c7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c7o ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/SRP54_ECOLI SRP54_ECOLI] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.<ref>PMID:2171778</ref> <ref>PMID:1279430</ref> <ref>PMID:1331806</ref> <ref>PMID:9305630</ref> <ref>PMID:11735405</ref> <ref>PMID:11741850</ref> <ref>PMID:15140892</ref>  

*[[Signal recognition particle 3D structures|Signal recognition particle 3D structures]]

*[[Signal recognition particle receptor 3D structures|Signal recognition particle receptor 3D structures]]

[[Category: Escherichia coli K-12]]

[[Category: Large Structures]]

[[Category: Ataide SF]]

[[Category: Ban N]]

[[Category: Schmitz N]]

[[Category: Shan SO]]

[[Category: Shen K]]

[[Category: Voigts-Hoffmann F]]