4bz8: Difference between revisions

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==Crystal structure of Schistosoma mansoni HDAC8 complexed with J1038==
==Crystal structure of Schistosoma mansoni HDAC8 complexed with J1038==
<StructureSection load='4bz8' size='340' side='right' caption='[[4bz8]], [[Resolution|resolution]] 2.21&Aring;' scene=''>
<StructureSection load='4bz8' size='340' side='right'caption='[[4bz8]], [[Resolution|resolution]] 2.21&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4bz8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BZ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BZ8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4bz8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BZ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BZ8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=J38:(2R)-2-METHYL-3-OXO-4H-1,4-BENZOTHIAZINE-6-CARBOHYDROXAMIC+ACID'>J38</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.21&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bz5|4bz5]], [[4bz6|4bz6]], [[4bz7|4bz7]], [[4bz9|4bz9]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=J38:(2R)-2-METHYL-3-OXO-4H-1,4-BENZOTHIAZINE-6-CARBOHYDROXAMIC+ACID'>J38</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bz8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bz8 RCSB], [http://www.ebi.ac.uk/pdbsum/4bz8 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bz8 OCA], [https://pdbe.org/4bz8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bz8 RCSB], [https://www.ebi.ac.uk/pdbsum/4bz8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bz8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A5H660_SCHMA A5H660_SCHMA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4bz8" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Histone deacetylase|Histone deacetylase]]
*[[Histone deacetylase 3D structures|Histone deacetylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Schistosoma mansoni]]
[[Category: Schistosoma mansoni]]
[[Category: Marek, M]]
[[Category: Marek M]]
[[Category: Romier, C]]
[[Category: Romier C]]
[[Category: Hdac8]]
[[Category: Hydrolase]]
[[Category: Inhibitor]]
[[Category: Platyhelminth]]

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