4btl: Difference between revisions
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==Aromatic interactions in acetylcholinesterase-inhibitor complexes== | ==Aromatic interactions in acetylcholinesterase-inhibitor complexes== | ||
<StructureSection load='4btl' size='340' side='right' caption='[[4btl]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='4btl' size='340' side='right'caption='[[4btl]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4btl]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4btl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BTL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BTL FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GZ:4-(2-CHLORO-6-NITROPHENOXY)-N-[2-(DIETHYLAMINO)ETHYL]BENZENESULFONAMIDE'>5GZ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PE3:3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL'>PE3</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GZ:4-(2-CHLORO-6-NITROPHENOXY)-N-[2-(DIETHYLAMINO)ETHYL]BENZENESULFONAMIDE'>5GZ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PE3:3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL'>PE3</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4btl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4btl OCA], [https://pdbe.org/4btl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4btl RCSB], [https://www.ebi.ac.uk/pdbsum/4btl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4btl ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ACES_MOUSE ACES_MOUSE] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Acetylcholinesterase | *[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Akfur | [[Category: Akfur C]] | ||
[[Category: Allgardsson | [[Category: Allgardsson A]] | ||
[[Category: Andersson | [[Category: Andersson CD]] | ||
[[Category: Berg | [[Category: Berg L]] | ||
[[Category: Ekstrom | [[Category: Ekstrom F]] | ||
[[Category: Engdahl | [[Category: Engdahl C]] | ||
[[Category: Forsgren | [[Category: Forsgren N]] | ||
[[Category: Linusson | [[Category: Linusson A]] | ||
[[Category: Qian | [[Category: Qian W]] | ||