4bli: Difference between revisions

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-'''Unreleased structure'''
-The entry 4bli is ON HOLD  until Paper Publication
+==Galectin-3c in complex with Bisamido-thiogalactoside derivate 1==
+<StructureSection load='4bli' size='340' side='right'caption='[[4bli]], [[Resolution|resolution]] 1.08&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4bli]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BLI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BLI FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.08&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GMK:(3-DEOXY-3-(3-METHOXY-BENZAMIDO)-B-D-GALACTOPYRANOSYL)-(3-DEOXY-3-(3-METHOXY-BENZAMIDO)-2-O-SULFO-B-D-GALACTOPYRANOSYL)-SULFIDE'>GMK</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bli OCA], [https://pdbe.org/4bli PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bli RCSB], [https://www.ebi.ac.uk/pdbsum/4bli PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bli ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/LEG3_HUMAN LEG3_HUMAN] Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.<ref>PMID:15181153</ref> <ref>PMID:19594635</ref> <ref>PMID:19616076</ref>
-Authors: Noresson, A.L., Oberg, C.T., Engstrom, O., Hakansson, M., Logan, D.T., Leffler, H., Nilsson, U.J.
+==See Also==
+*[[Galectin 3D structures|Galectin 3D structures]]
-Description: Galectin-3c in complex with Bisamido-thiogalactoside derivate 1
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Engstrom O]]
+[[Category: Hakansson M]]
+[[Category: Leffler H]]
+[[Category: Logan DT]]
+[[Category: Nilsson UJ]]
+[[Category: Noresson AL]]
+[[Category: Oberg CT]]