4bd0: Difference between revisions
No edit summary |
No edit summary |
||
| (3 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==X-ray structure of a perdeuterated Toho-1 R274N R276N double mutant Beta-lactamase in complex with a fully deuterated boronic acid (BZB)== | ==X-ray structure of a perdeuterated Toho-1 R274N R276N double mutant Beta-lactamase in complex with a fully deuterated boronic acid (BZB)== | ||
<StructureSection load='4bd0' size='340' side='right' caption='[[4bd0]], [[Resolution|resolution]] 1.21Å' scene=''> | <StructureSection load='4bd0' size='340' side='right'caption='[[4bd0]], [[Resolution|resolution]] 1.21Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4bd0]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4bd0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21 Escherichia coli BL21]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BD0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BD0 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.207Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BZB:BENZO[B]THIOPHENE-2-BORONIC+ACID'>BZB</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bd0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bd0 OCA], [https://pdbe.org/4bd0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bd0 RCSB], [https://www.ebi.ac.uk/pdbsum/4bd0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bd0 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/BLT1_ECOLX BLT1_ECOLX] Has strong cefotaxime-hydrolyzing activity. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 22: | Line 21: | ||
==See Also== | ==See Also== | ||
*[[Beta-lactamase|Beta-lactamase]] | *[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli BL21]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Coates | [[Category: Coates L]] | ||
[[Category: Ng | [[Category: Ng JD]] | ||
[[Category: Ostermann | [[Category: Ostermann A]] | ||
[[Category: Schrader | [[Category: Schrader TE]] | ||
[[Category: Standaert | [[Category: Standaert RF]] | ||
[[Category: Tomanicek | [[Category: Tomanicek SJ]] | ||
[[Category: Weiss | [[Category: Weiss KL]] | ||