4bbk: Difference between revisions

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OCA

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 <StructureSection load='4bbk' size='340' side='right'caption='[[4bbk]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4bbk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BBK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BBK FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4bbk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BBK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BBK FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bbk OCA], [http://pdbe.org/4bbk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bbk RCSB], [http://www.ebi.ac.uk/pdbsum/4bbk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bbk ProSAT]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bbk OCA], [https://pdbe.org/4bbk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bbk RCSB], [https://www.ebi.ac.uk/pdbsum/4bbk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bbk ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/FERM1_MOUSE FERM1_MOUSE] Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity).
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 21: / Line 24: @@
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Lk3 transgenic mice]]
+[[Category: Mus musculus]]
-[[Category: Bird, L E]]
+[[Category: Bird LE]]
-[[Category: Brahme, N N]]
+[[Category: Brahme NN]]
-[[Category: Calderwood, D A]]
+[[Category: Calderwood DA]]
-[[Category: Colibus, L De]]
+[[Category: De Colibus L]]
-[[Category: Gilbert, R J.C]]
+[[Category: Gilbert RJC]]
-[[Category: Lumb, C N]]
+[[Category: Lumb CN]]
-[[Category: Owens, R J]]
+[[Category: Owens RJ]]
-[[Category: Sansom, M S.P]]
+[[Category: Sansom MSP]]
-[[Category: Yates, L A]]
+[[Category: Yates LA]]
-[[Category: Zalyte, R]]
+[[Category: Zalyte R]]
-[[Category: Cell adhesion]]
-[[Category: Ph domain]]