4avh: Difference between revisions

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 ==Structure of the FimH lectin domain in the trigonal space group, in complex with a thioalkyl alpha-D-mannoside at 2.1 A resolution==
-<StructureSection load='4avh' size='340' side='right' caption='[[4avh]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+<StructureSection load='4avh' size='340' side='right'caption='[[4avh]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4avh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecout Ecout]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AVH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AVH FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4avh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_UTI89 Escherichia coli UTI89]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AVH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AVH FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FK9:PROPYL+THIOPROPYL+ALPHA-D-MANNOPYRANOSIDE'>FK9</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.105&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4att|4att]], [[4auj|4auj]], [[4auu|4auu]], [[4auy|4auy]], [[4av0|4av0]], [[4av4|4av4]], [[4av5|4av5]], [[4avi|4avi]], [[4avj|4avj]], [[4avk|4avk]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FK9:PROPYL+THIOPROPYL+ALPHA-D-MANNOPYRANOSIDE'>FK9</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4avh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4avh OCA], [http://pdbe.org/4avh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4avh RCSB], [http://www.ebi.ac.uk/pdbsum/4avh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4avh ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4avh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4avh OCA], [https://pdbe.org/4avh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4avh RCSB], [https://www.ebi.ac.uk/pdbsum/4avh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4avh ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 17: / Line 19: @@
 </div>
 <div class="pdbe-citations 4avh" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Adhesin 3D structures|Adhesin 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Ecout]]
+[[Category: Escherichia coli UTI89]]
-[[Category: Bouckaert, J]]
+[[Category: Large Structures]]
-[[Category: Lahmann, M]]
+[[Category: Bouckaert J]]
-[[Category: Oscarson, S]]
+[[Category: Lahmann M]]
-[[Category: Remaut, H]]
+[[Category: Oscarson S]]
-[[Category: Roy, R]]
+[[Category: Remaut H]]
-[[Category: Touaibia, M]]
+[[Category: Roy R]]
-[[Category: Vaucher, J]]
+[[Category: Touaibia M]]
-[[Category: Wellens, A]]
+[[Category: Vaucher J]]
-[[Category: Bacterial adhesin]]
+[[Category: Wellens A]]
-[[Category: Cell adhesion]]
-[[Category: Type 1 fimbriae]]
-[[Category: Urinary tract infection]]
-[[Category: Variable immunoglobulin fold]]