4akc: Difference between revisions
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==Structure of Galactose Binding lectin from Champedak (CGB) with Gal(beta)1,3-GalNac== | ==Structure of Galactose Binding lectin from Champedak (CGB) with Gal(beta)1,3-GalNac== | ||
<StructureSection load='4akc' size='340' side='right' caption='[[4akc]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='4akc' size='340' side='right'caption='[[4akc]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4akc]] is a 8 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4akc]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AKC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AKC FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>< | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=PRD_900084:Thomsen-Friedenreich+antigen'>PRD_900084</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4akc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4akc OCA], [https://pdbe.org/4akc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4akc RCSB], [https://www.ebi.ac.uk/pdbsum/4akc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4akc ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/LECA_ARTIN LECA_ARTIN] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 4akc" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4akc" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Agglutinin 3D structures|Agglutinin 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Artocarpus integer]] | [[Category: Artocarpus integer]] | ||
[[Category: Abdul-Rahman | [[Category: Large Structures]] | ||
[[Category: Cogdell | [[Category: Abdul-Rahman PS]] | ||
[[Category: Gabrielsen | [[Category: Cogdell RJ]] | ||
[[Category: Hashim | [[Category: Gabrielsen M]] | ||
[[Category: Othman | [[Category: Hashim OH]] | ||
[[Category: Othman S]] | |||