4ahn: Difference between revisions

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 <StructureSection load='4ahn' size='340' side='right'caption='[[4ahn]], [[Resolution|resolution]] 2.98&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4ahn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AHN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AHN FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4ahn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AHN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AHN FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.977&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hby|1hby]], [[1h53|1h53]], [[2ang|2ang]], [[1un3|1un3]], [[1a4y|1a4y]], [[1b1j|1b1j]], [[1un4|1un4]], [[1un5|1un5]], [[1h0d|1h0d]], [[1b1e|1b1e]], [[1k59|1k59]], [[1k5b|1k5b]], [[1k58|1k58]], [[1ang|1ang]], [[1k5a|1k5a]], [[1awz|1awz]], [[1b1i|1b1i]], [[1h52|1h52]], [[4ahj|4ahj]], [[4ahk|4ahk]], [[4ahe|4ahe]], [[4ahm|4ahm]], [[4ahf|4ahf]], [[4ahd|4ahd]], [[4ahg|4ahg]], [[4ahi|4ahi]], [[4ahh|4ahh]], [[4ahl|4ahl]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ahn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ahn OCA], [http://pdbe.org/4ahn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ahn RCSB], [http://www.ebi.ac.uk/pdbsum/4ahn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ahn ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ahn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ahn OCA], [https://pdbe.org/4ahn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ahn RCSB], [https://www.ebi.ac.uk/pdbsum/4ahn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ahn ProSAT]</span></td></tr>
 </table>
 == Disease ==
-[[http://www.uniprot.org/uniprot/ANGI_HUMAN ANGI_HUMAN]] Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9) [MIM:[http://omim.org/entry/611895 611895]]. ALS is a degenerative disorder of motor neurons in the cortex, brain stem and spinal cord. ALS is characterized by muscular weakness and atrophy.<ref>PMID:17886298</ref> <ref>PMID:15557516</ref> <ref>PMID:16501576</ref> <ref>PMID:17900154</ref> <ref>PMID:18087731</ref> <ref>PMID:17703939</ref>
+[https://www.uniprot.org/uniprot/ANGI_HUMAN ANGI_HUMAN] Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9) [MIM:[https://omim.org/entry/611895 611895]. ALS is a degenerative disorder of motor neurons in the cortex, brain stem and spinal cord. ALS is characterized by muscular weakness and atrophy.<ref>PMID:17886298</ref> <ref>PMID:15557516</ref> <ref>PMID:16501576</ref> <ref>PMID:17900154</ref> <ref>PMID:18087731</ref> <ref>PMID:17703939</ref>
 == Function ==
-[[http://www.uniprot.org/uniprot/ANGI_HUMAN ANGI_HUMAN]] May function as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.<ref>PMID:1400510</ref> <ref>PMID:19354288</ref>
+[https://www.uniprot.org/uniprot/ANGI_HUMAN ANGI_HUMAN] May function as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.<ref>PMID:1400510</ref> <ref>PMID:19354288</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 23: / Line 23: @@
 ==See Also==
-*[[Ribonuclease|Ribonuclease]]
+*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Acharya, K R]]
+[[Category: Large Structures]]
-[[Category: Ferguson, R]]
+[[Category: Acharya KR]]
-[[Category: Pham, T]]
+[[Category: Ferguson R]]
-[[Category: Saha, S]]
+[[Category: Pham T]]
-[[Category: Subramanian, V]]
+[[Category: Saha S]]
-[[Category: Thiyagarajan, N]]
+[[Category: Subramanian V]]
-[[Category: Als neovascularisation]]
+[[Category: Thiyagarajan N]]
-[[Category: Ang]]
-[[Category: Hydrolase]]