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==Crystal structure of ammosamide 272:myosin-2 motor domain complex==
==Crystal structure of ammosamide 272:myosin-2 motor domain complex==
<StructureSection load='4ae3' size='340' side='right' caption='[[4ae3]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4ae3' size='340' side='right'caption='[[4ae3]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ae3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum_ax4 Dictyostelium discoideum ax4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AE3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AE3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ae3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum_AX4 Dictyostelium discoideum AX4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AE3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=27X:AMMOSAMIDE+272'>27X</scene>, <scene name='pdbligand=AOV:ADP+ORTHOVANADATE'>AOV</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mne|1mne]], [[1d1c|1d1c]], [[1w9l|1w9l]], [[1vom|1vom]], [[1mmn|1mmn]], [[2aka|2aka]], [[2jhr|2jhr]], [[2y8i|2y8i]], [[1w9j|1w9j]], [[2x9h|2x9h]], [[1fmv|1fmv]], [[1mma|1mma]], [[2xo8|2xo8]], [[1mmg|1mmg]], [[2y0r|2y0r]], [[1w9i|1w9i]], [[1mnd|1mnd]], [[1w9k|1w9k]], [[1jx2|1jx2]], [[1q5g|1q5g]], [[1d0y|1d0y]], [[1lvk|1lvk]], [[2jj9|2jj9]], [[2xel|2xel]], [[1jwy|1jwy]], [[1yv3|1yv3]], [[1d0x|1d0x]], [[1fmw|1fmw]], [[1d1b|1d1b]], [[1g8x|1g8x]], [[1d1a|1d1a]], [[1d0z|1d0z]], [[1mmd|1mmd]], [[2y9e|2y9e]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=27X:AMMOSAMIDE+272'>27X</scene>, <scene name='pdbligand=AOV:ADP+ORTHOVANADATE'>AOV</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Myosin_ATPase Myosin ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.1 3.6.4.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ae3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ae3 OCA], [https://pdbe.org/4ae3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ae3 RCSB], [https://www.ebi.ac.uk/pdbsum/4ae3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ae3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ae3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ae3 OCA], [http://pdbe.org/4ae3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ae3 RCSB], [http://www.ebi.ac.uk/pdbsum/4ae3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ae3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI]] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.  
[https://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.


==See Also==
==See Also==
*[[Myosin|Myosin]]
*[[Myosin 3D Structures|Myosin 3D Structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Dictyostelium discoideum ax4]]
[[Category: Dictyostelium discoideum AX4]]
[[Category: Myosin ATPase]]
[[Category: Large Structures]]
[[Category: Chinthalapudi, K]]
[[Category: Chinthalapudi K]]
[[Category: Fenical, W]]
[[Category: Fenical W]]
[[Category: Heissler, S M]]
[[Category: Heissler SM]]
[[Category: Manstein, D J]]
[[Category: Manstein DJ]]
[[Category: Actin binding]]
[[Category: Atpase]]
[[Category: Contractile protein]]
[[Category: Hydrolase]]
[[Category: Motor protein]]

Latest revision as of 14:24, 20 December 2023

Crystal structure of ammosamide 272:myosin-2 motor domain complexCrystal structure of ammosamide 272:myosin-2 motor domain complex

Structural highlights

4ae3 is a 1 chain structure with sequence from Dictyostelium discoideum AX4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.5Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MYS2_DICDI Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.

See Also

4ae3, resolution 2.50Å

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