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==Structure of the global transcription regulator FapR from Staphylococcus aureus==
==Structure of the global transcription regulator FapR from Staphylococcus aureus==
<StructureSection load='4a0x' size='340' side='right' caption='[[4a0x]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='4a0x' size='340' side='right'caption='[[4a0x]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4a0x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A0X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A0X FirstGlance]. <br>
<table><tr><td colspan='2'>[[4a0x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A0X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A0X FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4a0y|4a0y]], [[4a0z|4a0z]], [[4a12|4a12]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a0x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a0x OCA], [http://pdbe.org/4a0x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4a0x RCSB], [http://www.ebi.ac.uk/pdbsum/4a0x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4a0x ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a0x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a0x OCA], [https://pdbe.org/4a0x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a0x RCSB], [https://www.ebi.ac.uk/pdbsum/4a0x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a0x ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/D6UB50_STAAU D6UB50_STAAU]] Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.[HAMAP-Rule:MF_01814]  
[https://www.uniprot.org/uniprot/Q2FZ56_STAA8 Q2FZ56_STAA8] Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.[HAMAP-Rule:MF_01814]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Albanesi, D]]
[[Category: Large Structures]]
[[Category: Alzari, P M]]
[[Category: Staphylococcus aureus]]
[[Category: Buschiazzo, A]]
[[Category: Albanesi D]]
[[Category: Guerin, M E]]
[[Category: Alzari PM]]
[[Category: Mendoza, D de]]
[[Category: Buschiazzo A]]
[[Category: Lipid homeostasis]]
[[Category: Guerin ME]]
[[Category: Transcription]]
[[Category: De Mendoza D]]

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