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==CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH NPG AT 1.9 A RESOLUTION== | ==CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH NPG AT 1.9 A RESOLUTION== | ||
<StructureSection load='3zyf' size='340' side='right' caption='[[3zyf]], [[Resolution|resolution]] 1.94Å' scene=''> | <StructureSection load='3zyf' size='340' side='right'caption='[[3zyf]], [[Resolution|resolution]] 1.94Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3zyf]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3zyf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZYF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZYF FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.944Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=147:1-O-[P-NITROPHENYL]-BETA-D-GALACTOPYRANOSE'>147</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zyf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zyf OCA], [https://pdbe.org/3zyf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zyf RCSB], [https://www.ebi.ac.uk/pdbsum/3zyf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zyf ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity. | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Pseudomonas aeruginosa]] | [[Category: Large Structures]] | ||
[[Category: Bergmann | [[Category: Pseudomonas aeruginosa PAO1]] | ||
[[Category: Cacciarini | [[Category: Bergmann M]] | ||
[[Category: Camara | [[Category: Cacciarini M]] | ||
[[Category: Darbre | [[Category: Camara M]] | ||
[[Category: Garg | [[Category: Darbre T]] | ||
[[Category: Hurley | [[Category: Garg D]] | ||
[[Category: Kadam | [[Category: Hurley M]] | ||
[[Category: Nativi | [[Category: Kadam RU]] | ||
[[Category: Reymond | [[Category: Nativi C]] | ||
[[Category: Sattler | [[Category: Reymond J-L]] | ||
[[Category: Smyth | [[Category: Sattler M]] | ||
[[Category: Stocker | [[Category: Smyth AR]] | ||
[[Category: Swiderska | [[Category: Stocker A]] | ||
[[Category: Williams | [[Category: Swiderska MA]] | ||
[[Category: Williams P]] | |||
Latest revision as of 14:16, 20 December 2023
CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH NPG AT 1.9 A RESOLUTIONCRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH NPG AT 1.9 A RESOLUTION
Structural highlights
FunctionPA1L_PSEAE D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity. See Also |
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