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==CRYSTAL STRUCTURE OF PNEUMOCOCCAL SURFACE ANTIGEN PSAA WITH MANGANESE==
 
<StructureSection load='3ztt' size='340' side='right' caption='[[3ztt]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
==Crystal structure of pneumococcal surface antigen PsaA with manganese==
<StructureSection load='3ztt' size='340' side='right'caption='[[3ztt]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ztt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZTT FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ztt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZTT FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ztt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ztt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ztt RCSB], [http://www.ebi.ac.uk/pdbsum/3ztt PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<table>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ztt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ztt OCA], [https://pdbe.org/3ztt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ztt RCSB], [https://www.ebi.ac.uk/pdbsum/3ztt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ztt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MTSA_STRPN MTSA_STRPN] Part of an ATP-driven transport system for manganese. Also act as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in pathogenesis and infection.
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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A molecular mechanism for bacterial susceptibility to zinc.,McDevitt CA, Ogunniyi AD, Valkov E, Lawrence MC, Kobe B, McEwan AG, Paton JC PLoS Pathog. 2011 Nov;7(11):e1002357. Epub 2011 Nov 3. PMID:22072971<ref>PMID:22072971</ref>
A molecular mechanism for bacterial susceptibility to zinc.,McDevitt CA, Ogunniyi AD, Valkov E, Lawrence MC, Kobe B, McEwan AG, Paton JC PLoS Pathog. 2011 Nov;7(11):e1002357. Epub 2011 Nov 3. PMID:22072971<ref>PMID:22072971</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3ztt" style="background-color:#fffaf0;"></div>
==See Also==
*[[Adhesin 3D structures|Adhesin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Streptococcus pneumoniae]]
[[Category: Streptococcus pneumoniae]]
[[Category: Kobe, B.]]
[[Category: Kobe B]]
[[Category: Lawrence, M C.]]
[[Category: Lawrence MC]]
[[Category: Mcdevitt, C A.]]
[[Category: McDevitt CA]]
[[Category: Mcewan, A G.]]
[[Category: McEwan AG]]
[[Category: Ogunniyi, A D.]]
[[Category: Ogunniyi AD]]
[[Category: Paton, J C.]]
[[Category: Paton JC]]
[[Category: Valkov, E.]]
[[Category: Valkov E]]
[[Category: Metal binding protein]]

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