3zpr: Difference between revisions
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==Thermostabilised turkey beta1 adrenergic receptor with 4-methyl-2-(piperazin-1-yl) quinoline bound== | ==Thermostabilised turkey beta1 adrenergic receptor with 4-methyl-2-(piperazin-1-yl) quinoline bound== | ||
<StructureSection load='3zpr' size='340' side='right' caption='[[3zpr]], [[Resolution|resolution]] 2.70Å' scene=''> | <StructureSection load='3zpr' size='340' side='right'caption='[[3zpr]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3zpr]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3zpr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZPR FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2CV:HEGA-10'>2CV</scene>, <scene name='pdbligand=3WC:4-METHYL-2-(PIPERAZIN-1-YL)+QUINOLINE'>3WC</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2CV:HEGA-10'>2CV</scene>, <scene name='pdbligand=3WC:4-METHYL-2-(PIPERAZIN-1-YL)+QUINOLINE'>3WC</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpr OCA], [https://pdbe.org/3zpr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zpr RCSB], [https://www.ebi.ac.uk/pdbsum/3zpr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zpr ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ADRB1_MELGA ADRB1_MELGA] Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 21: | Line 21: | ||
==See Also== | ==See Also== | ||
*[[Adrenergic receptor|Adrenergic receptor]] | *[[Adrenergic receptor 3D structures|Adrenergic receptor 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Brown | [[Category: Meleagris gallopavo]] | ||
[[Category: Christopher | [[Category: Brown J]] | ||
[[Category: Congreve | [[Category: Christopher JA]] | ||
[[Category: Dore | [[Category: Congreve M]] | ||
[[Category: Errey | [[Category: Dore AS]] | ||
[[Category: Koglin | [[Category: Errey JC]] | ||
[[Category: Marshall | [[Category: Koglin M]] | ||
[[Category: Myszka | [[Category: Marshall FH]] | ||
[[Category: Tate | [[Category: Myszka DG]] | ||
[[Category: Tehan | [[Category: Tate CG]] | ||
[[Category: Warne | [[Category: Tehan B]] | ||
[[Category: Warne T]] | |||