2yht: Difference between revisions

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-[[Image:2yht.jpg|left|200px]]
-<!--
+==Crystal structure of Hfq riboregulator from E. coli (P1 space group)==
-The line below this paragraph, containing "STRUCTURE_2yht", creates the "Structure Box" on the page.
+<StructureSection load='2yht' size='340' side='right'caption='[[2yht]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2yht]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YHT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YHT FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yht FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yht OCA], [https://pdbe.org/2yht PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yht RCSB], [https://www.ebi.ac.uk/pdbsum/2yht PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yht ProSAT]</span></td></tr>
-{{STRUCTURE_2yht|  PDB=2yht  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/HFQ_ECOLI HFQ_ECOLI] RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Involved in the regulation of stress responses mediated by the sigma factors RpoS, sigma-E and sigma-32. Binds with high specificity to tRNAs. In vitro, stimulates synthesis of long tails by poly(A) polymerase I. Required for RNA phage Qbeta replication.<ref>PMID:805130</ref> <ref>PMID:10677490</ref> <ref>PMID:11222598</ref> <ref>PMID:17158661</ref> <ref>PMID:19909729</ref>   Seems to play a role in persister cell formation; upon overexpression decreases persister cell formation while deletion increases persister formation.<ref>PMID:805130</ref> <ref>PMID:10677490</ref> <ref>PMID:11222598</ref> <ref>PMID:17158661</ref> <ref>PMID:19909729</ref>
-===CRYSTAL STRUCTURE OF HFQ RIBOREGULATOR FROM E. COLI (P1 SPACE GROUP)===
+==See Also==
+*[[Protein Hfq 3D structures|Protein Hfq 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_12853626}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 12853626 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_12853626}}
-==About this Structure==
-[[2yht]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YHT OCA].
-==Reference==
-<ref group="xtra">PMID:012853626</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
-[[Category: Basquin, J.]]
+[[Category: Large Structures]]
-[[Category: Sauter, C.]]
+[[Category: Basquin J]]
-[[Category: Chaperone]]
+[[Category: Sauter C]]
-[[Category: Rna chaperone]]