2yhf: Difference between revisions

<table><tr><td colspan='2'>[[2yhf]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YHF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YHF FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yhf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yhf OCA], [https://pdbe.org/2yhf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yhf RCSB], [https://www.ebi.ac.uk/pdbsum/2yhf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yhf ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/CLC5A_HUMAN CLC5A_HUMAN] Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation (By similarity). Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.<ref>PMID:10449773</ref> <ref>PMID:18496526</ref>  

[[Category: Homo sapiens]]

[[Category: Hall BA]]

[[Category: Lebedev AA]]

[[Category: Murshudov GM]]

[[Category: O'Callaghan CA]]

[[Category: Vagin AA]]

[[Category: Watson AA]]