2yhf: Difference between revisions

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-==1.9 ANGSTROM CRYSTAL STRUCTURE OF CLEC5A==
-<StructureSection load='2yhf' size='340' side='right' caption='[[2yhf]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
+==1.9 Angstrom Crystal Structure of CLEC5A==
+<StructureSection load='2yhf' size='340' side='right'caption='[[2yhf]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2yhf]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YHF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YHF FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2yhf]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YHF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YHF FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yhf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yhf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yhf RCSB], [http://www.ebi.ac.uk/pdbsum/2yhf PDBsum]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yhf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yhf OCA], [https://pdbe.org/2yhf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yhf RCSB], [https://www.ebi.ac.uk/pdbsum/2yhf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yhf ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/CLC5A_HUMAN CLC5A_HUMAN] Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation (By similarity). Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.<ref>PMID:10449773</ref> <ref>PMID:18496526</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 13: / Line 17: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 2yhf" style="background-color:#fffaf0;"></div>
 == References ==
 <references/>
@@ Line 18: / Line 23: @@
 </StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Callaghan, C A.O]]
+[[Category: Large Structures]]
-[[Category: Hall, B A]]
+[[Category: Hall BA]]
-[[Category: Lebedev, A A]]
+[[Category: Lebedev AA]]
-[[Category: Murshudov, G M]]
+[[Category: Murshudov GM]]
-[[Category: Vagin, A A]]
+[[Category: O'Callaghan CA]]
-[[Category: Watson, A A]]
+[[Category: Vagin AA]]
-[[Category: Immune system]]
+[[Category: Watson AA]]