2y90: Difference between revisions

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-[[Image:2y90.png|left|200px]]
-{{STRUCTURE_2y90|  PDB=2y90  |  SCENE=  }}
+==Crystal structure of Hfq riboregulator from E. coli (P6 space group)==
+<StructureSection load='2y90' size='340' side='right'caption='[[2y90]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2y90]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y90 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.252&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y90 OCA], [https://pdbe.org/2y90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y90 RCSB], [https://www.ebi.ac.uk/pdbsum/2y90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y90 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/HFQ_ECOLI HFQ_ECOLI] RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Involved in the regulation of stress responses mediated by the sigma factors RpoS, sigma-E and sigma-32. Binds with high specificity to tRNAs. In vitro, stimulates synthesis of long tails by poly(A) polymerase I. Required for RNA phage Qbeta replication.<ref>PMID:805130</ref> <ref>PMID:10677490</ref> <ref>PMID:11222598</ref> <ref>PMID:17158661</ref> <ref>PMID:19909729</ref>   Seems to play a role in persister cell formation; upon overexpression decreases persister cell formation while deletion increases persister formation.<ref>PMID:805130</ref> <ref>PMID:10677490</ref> <ref>PMID:11222598</ref> <ref>PMID:17158661</ref> <ref>PMID:19909729</ref>
-===CRYSTAL STRUCTURE OF HFQ RIBOREGULATOR FROM E. COLI (P6 SPACE GROUP)===
+==See Also==
+*[[Protein Hfq 3D structures|Protein Hfq 3D structures]]
-{{ABSTRACT_PUBMED_12853626}}
+== References ==
+<references/>
-==About this Structure==
+__TOC__
-[[2y90]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y90 OCA].
+</StructureSection>
-==Reference==
-<ref group="xtra">PMID:012853626</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
-[[Category: Basquin, J.]]
+[[Category: Large Structures]]
-[[Category: Sauter, C.]]
+[[Category: Basquin J]]
-[[Category: Rna chaperone]]
+[[Category: Sauter C]]
-[[Category: Rna-binding protein]]
-[[Category: Sm-like]]