2y2d: Difference between revisions
No edit summary |
No edit summary |
||
| (5 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
== | |||
<StructureSection load='2y2d' size='340' side='right' caption='[[2y2d]], [[Resolution|resolution]] 2.00Å' scene=''> | ==crystal structure of AmpD holoenzyme== | ||
<StructureSection load='2y2d' size='340' side='right'caption='[[2y2d]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2y2d]] is a 3 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2y2d]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y2D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y2D FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr><td class="sblockLbl"><b> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y2d OCA], [https://pdbe.org/2y2d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y2d RCSB], [https://www.ebi.ac.uk/pdbsum/2y2d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y2d ProSAT]</span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </table> | ||
<table> | == Function == | ||
[https://www.uniprot.org/uniprot/AMPD_CITFR AMPD_CITFR] Involved in both cell wall peptidoglycans recycling and beta-lactamase induction. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 14: | Line 16: | ||
Crystal Structures of Bacterial Peptidoglycan Amidase AmpD and an Unprecedented Activation Mechanism.,Carrasco-Lopez C, Rojas-Altuve A, Zhang W, Hesek D, Lee M, Barbe S, Andre I, Ferrer P, Silva-Martin N, Castro GR, Martinez-Ripoll M, Mobashery S, Hermoso JA J Biol Chem. 2011 Sep 9;286(36):31714-22. Epub 2011 Jul 20. PMID:21775432<ref>PMID:21775432</ref> | Crystal Structures of Bacterial Peptidoglycan Amidase AmpD and an Unprecedented Activation Mechanism.,Carrasco-Lopez C, Rojas-Altuve A, Zhang W, Hesek D, Lee M, Barbe S, Andre I, Ferrer P, Silva-Martin N, Castro GR, Martinez-Ripoll M, Mobashery S, Hermoso JA J Biol Chem. 2011 Sep 9;286(36):31714-22. Epub 2011 Jul 20. PMID:21775432<ref>PMID:21775432</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2y2d" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 21: | Line 24: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Citrobacter freundii]] | [[Category: Citrobacter freundii]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Andre | [[Category: Andre I]] | ||
[[Category: Barbe | [[Category: Barbe S]] | ||
[[Category: Carrasco-Lopez | [[Category: Carrasco-Lopez C]] | ||
[[Category: Hermoso | [[Category: Hermoso JA]] | ||
[[Category: Hesek | [[Category: Hesek D]] | ||
[[Category: Lee | [[Category: Lee M]] | ||
[[Category: Martinez-Ripoll | [[Category: Martinez-Ripoll M]] | ||
[[Category: Mobashery | [[Category: Mobashery S]] | ||
[[Category: Rojas-Altuve | [[Category: Rojas-Altuve A]] | ||
[[Category: Silva-Martin | [[Category: Silva-Martin N]] | ||
[[Category: Zhang | [[Category: Zhang W]] | ||