2xu7: Difference between revisions

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-==STRUCTURAL BASIS FOR RBAP48 BINDING TO FOG-1==
-<StructureSection load='2xu7' size='340' side='right' caption='[[2xu7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
+==Structural basis for RbAp48 binding to FOG-1==
+<StructureSection load='2xu7' size='340' side='right'caption='[[2xu7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2xu7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XU7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XU7 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2xu7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XU7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XU7 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xu7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xu7 RCSB], [http://www.ebi.ac.uk/pdbsum/2xu7 PDBsum]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xu7 OCA], [https://pdbe.org/2xu7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xu7 RCSB], [https://www.ebi.ac.uk/pdbsum/2xu7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xu7 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/RBBP4_HUMAN RBBP4_HUMAN] Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.<ref>PMID:10866654</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 14: / Line 18: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 2xu7" style="background-color:#fffaf0;"></div>
 ==See Also==
-*[[Retinoblastoma-binding protein|Retinoblastoma-binding protein]]
+*[[Retinoblastoma-binding protein 3D structures|Retinoblastoma-binding protein 3D structures]]
 == References ==
 <references/>
@@ Line 22: / Line 27: @@
 </StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Blobel, G A.]]
+[[Category: Large Structures]]
-[[Category: Laue, E D.]]
+[[Category: Blobel GA]]
-[[Category: Lejon, S.]]
+[[Category: Laue ED]]
-[[Category: Mackay, J P.]]
+[[Category: Lejon S]]
-[[Category: Murthy, A.]]
+[[Category: Mackay JP]]
-[[Category: Murzina, N V.]]
+[[Category: Murthy A]]
-[[Category: Thong, S Y.]]
+[[Category: Murzina NV]]
-[[Category: Chromatin remodelling]]
+[[Category: Thong SY]]
-[[Category: Corepressor]]
-[[Category: Gata1-mediated repression]]
-[[Category: Histone chaperone]]
-[[Category: Nurd complex]]
-[[Category: Transcription]]