2xn3: Difference between revisions

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-==CRYSTAL STRUCTURE OF THYROXINE-BINDING GLOBULIN COMPLEXED WITH MEFENAMIC ACID==
+==Crystal structure of thyroxine-binding globulin complexed with mefenamic acid==
-<StructureSection load='2xn3' size='340' side='right' caption='[[2xn3]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
+<StructureSection load='2xn3' size='340' side='right'caption='[[2xn3]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2xn3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XN3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XN3 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2xn3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XN3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XN3 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ID8:2-[(2,3-DIMETHYLPHENYL)AMINO]BENZOIC+ACID'>ID8</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ceo|2ceo]], [[2xn7|2xn7]], [[2xn5|2xn5]], [[2xn6|2xn6]], [[2riw|2riw]], [[2riv|2riv]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ID8:2-[(2,3-DIMETHYLPHENYL)AMINO]BENZOIC+ACID'>ID8</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xn3 OCA], [http://pdbe.org/2xn3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xn3 RCSB], [http://www.ebi.ac.uk/pdbsum/2xn3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xn3 ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xn3 OCA], [https://pdbe.org/2xn3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xn3 RCSB], [https://www.ebi.ac.uk/pdbsum/2xn3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xn3 ProSAT]</span></td></tr>
 </table>
 == Disease ==
-[[http://www.uniprot.org/uniprot/THBG_HUMAN THBG_HUMAN]] Defects in SERPINA7 are a cause of thyroxine-binding globulin deficiency (TBG deficiency) [MIM:[http://omim.org/entry/314200 314200]]. Mutations in the SERPINA7 gene can result as a whole spectrum of deficiencies, characterized by either reduced or increased TBG levels in the serum. Patients show, respectively, reduced or elevated protein-bound iodine but are euthyroid.
+[https://www.uniprot.org/uniprot/THBG_HUMAN THBG_HUMAN] Defects in SERPINA7 are a cause of thyroxine-binding globulin deficiency (TBG deficiency) [MIM:[https://omim.org/entry/314200 314200]. Mutations in the SERPINA7 gene can result as a whole spectrum of deficiencies, characterized by either reduced or increased TBG levels in the serum. Patients show, respectively, reduced or elevated protein-bound iodine but are euthyroid.
 == Function ==
-[[http://www.uniprot.org/uniprot/THBG_HUMAN THBG_HUMAN]] Major thyroid hormone transport protein in serum.
+[https://www.uniprot.org/uniprot/THBG_HUMAN THBG_HUMAN] Major thyroid hormone transport protein in serum.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 23: / Line 23: @@
 ==See Also==
-*[[Hormone|Hormone]]
+*[[Serpin 3D structures|Serpin 3D structures]]
-*[[Serpin|Serpin]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Qi, X]]
+[[Category: Large Structures]]
-[[Category: Wei, Z]]
+[[Category: Qi X]]
-[[Category: Yan, Y]]
+[[Category: Wei Z]]
-[[Category: Zhou, A]]
+[[Category: Yan Y]]
-[[Category: Cleaved protein]]
+[[Category: Zhou A]]
-[[Category: Transport]]