2xa3: Difference between revisions

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==CRYSTAL STRUCTURE OF THE BROADLY NEUTRALIZING LLAMA VHH D7 AND ITS MODE OF HIV-1 GP120 INTERACTION==
 
<StructureSection load='2xa3' size='340' side='right' caption='[[2xa3]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
==crystal structure of the broadly neutralizing llama VHH D7 and its mode of HIV-1 gp120 interaction==
<StructureSection load='2xa3' size='340' side='right'caption='[[2xa3]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xa3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XA3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XA3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2xa3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XA3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XA3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xa3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xa3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xa3 RCSB], [http://www.ebi.ac.uk/pdbsum/2xa3 PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xa3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xa3 OCA], [https://pdbe.org/2xa3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xa3 RCSB], [https://www.ebi.ac.uk/pdbsum/2xa3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xa3 ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xa/2xa3_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xa/2xa3_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2xa3 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2xa3" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Antibody|Antibody]]
*[[Antibody 3D structures|Antibody 3D structures]]
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Lama glama]]
[[Category: Lama glama]]
[[Category: Belrhali, H]]
[[Category: Large Structures]]
[[Category: Dehaard, H]]
[[Category: Belrhali H]]
[[Category: Forsman, A]]
[[Category: Forsman A]]
[[Category: Gorlani, A]]
[[Category: Gorlani A]]
[[Category: Hinz, A]]
[[Category: Hinz A]]
[[Category: Koh, W]]
[[Category: Koh W]]
[[Category: Lutjehulsik, D]]
[[Category: Lutje Hulsik D]]
[[Category: Verrips, T]]
[[Category: Verrips T]]
[[Category: Weiss, R A]]
[[Category: Weiss RA]]
[[Category: Weissenhorn, W]]
[[Category: Weissenhorn W]]
[[Category: Immune system]]
[[Category: De Haard H]]

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