2x6b: Difference between revisions
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<StructureSection load='2x6b' size='340' side='right'caption='[[2x6b]], [[Resolution|resolution]] 3.30Å' scene=''> | <StructureSection load='2x6b' size='340' side='right'caption='[[2x6b]], [[Resolution|resolution]] 3.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2x6b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2x6b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X6B FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BA:BARIUM+ION'>BA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BA:BARIUM+ION'>BA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6b OCA], [https://pdbe.org/2x6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x6b RCSB], [https://www.ebi.ac.uk/pdbsum/2x6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x6b ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6b OCA], [https://pdbe.org/2x6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x6b RCSB], [https://www.ebi.ac.uk/pdbsum/2x6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x6b ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/IRK10_MAGMG IRK10_MAGMG] Inward rectifier potassium channel that mediates potassium uptake into the cell. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification may be achieved by the blockage of outward current by cytoplasmic divalent metal ions and polyamines. Complements an E.coli mutant that is defective in K(+) uptake.<ref>PMID:20876570</ref> <ref>PMID:20564790</ref> <ref>PMID:22231399</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Magnetospirillum magnetotacticum]] | ||
[[Category: | [[Category: Caputo AT]] | ||
[[Category: | [[Category: Clarke OB]] | ||
[[Category: | [[Category: Gulbis JM]] | ||
[[Category: | [[Category: Hill AP]] | ||
[[Category: | [[Category: Smith BJ]] | ||
[[Category: | [[Category: Vandenberg JI]] | ||