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==2.9 A RESOLUTION STRUCTURE OF MALATE DEHYDROGENASE FROM ARCHAEOGLOBUS FULGIDUS IN COMPLEX WITH NADH==
==2.9 A RESOLUTION STRUCTURE OF MALATE DEHYDROGENASE FROM ARCHAEOGLOBUS FULGIDUS IN COMPLEX WITH NADH==
<StructureSection load='2x0i' size='340' side='right' caption='[[2x0i]], [[Resolution|resolution]] 2.91&Aring;' scene=''>
<StructureSection load='2x0i' size='340' side='right'caption='[[2x0i]], [[Resolution|resolution]] 2.91&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2x0i]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcfu Arcfu]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ojs 1ojs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X0I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X0I FirstGlance]. <br>
<table><tr><td colspan='2'>[[2x0i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_DSM_4304 Archaeoglobus fulgidus DSM 4304]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ojs 1ojs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X0I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X0I FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.91&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2x06|2x06]], [[2x0j|2x0j]], [[2x0n|2x0n]], [[2x0r|2x0r]], [[2x0s|2x0s]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x0i OCA], [https://pdbe.org/2x0i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x0i RCSB], [https://www.ebi.ac.uk/pdbsum/2x0i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x0i ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x0i OCA], [http://pdbe.org/2x0i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x0i RCSB], [http://www.ebi.ac.uk/pdbsum/2x0i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x0i ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MDH_ARCFU MDH_ARCFU]] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_00487]  
[https://www.uniprot.org/uniprot/MDH_ARCFU MDH_ARCFU] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_00487]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arcfu]]
[[Category: Archaeoglobus fulgidus DSM 4304]]
[[Category: Malate dehydrogenase]]
[[Category: Large Structures]]
[[Category: Birkeland, N K]]
[[Category: Birkeland N-K]]
[[Category: Irimia, A]]
[[Category: Irimia A]]
[[Category: Karshikoff, A]]
[[Category: Karshikoff A]]
[[Category: Ladenstein, R]]
[[Category: Ladenstein R]]
[[Category: Lien, T]]
[[Category: Lien T]]
[[Category: Madern, D]]
[[Category: Madern D]]
[[Category: Tibbelin, G]]
[[Category: Tibbelin G]]
[[Category: Vellieux, F M.D]]
[[Category: Vellieux FMD]]
[[Category: Zaccai, G]]
[[Category: Zaccai G]]
[[Category: Hyperthermophilic]]
[[Category: Oxidoreductase]]
[[Category: Tricarboxylic acid cycle]]

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