2wwm: Difference between revisions

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 <StructureSection load='2wwm' size='340' side='right'caption='[[2wwm]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2wwm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WWM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WWM FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2wwm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WWM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WWM FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1tnn|1tnn]], [[1ncu|1ncu]], [[2j8o|2j8o]], [[1bpv|1bpv]], [[2j8h|2j8h]], [[2cpc|2cpc]], [[2wp3|2wp3]], [[1nct|1nct]], [[2wwk|2wwk]], [[2bk8|2bk8]], [[1tiu|1tiu]], [[2f8v|2f8v]], [[1tit|1tit]], [[1waa|1waa]], [[2a38|2a38]], [[1tnm|1tnm]], [[1g1c|1g1c]], [[1tki|1tki]], [[1ya5|1ya5]]</div></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wwm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wwm OCA], [https://pdbe.org/2wwm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wwm RCSB], [https://www.ebi.ac.uk/pdbsum/2wwm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wwm ProSAT]</span></td></tr>
 </table>
+== Disease ==
+[https://www.uniprot.org/uniprot/OBSL1_HUMAN OBSL1_HUMAN] Defects in OBSL1 are the cause of 3M syndrome type 2 (3M2) [MIM:[https://omim.org/entry/612921 612921]. An autosomal recessive disorder characterized by severe pre- and postnatal growth retardation, facial dysmorphism, large head circumference, and normal intelligence and endocrine function. Skeletal changes include long slender tubular bones and tall vertebral bodies.<ref>PMID:19481195</ref>
+== Function ==
+[https://www.uniprot.org/uniprot/OBSL1_HUMAN OBSL1_HUMAN]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 30: / Line 33: @@
 ==See Also==
 *[[Obscurin|Obscurin]]
-*[[Titin|Titin]]
+*[[Titin 3D structures|Titin 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Non-specific serine/threonine protein kinase]]
+[[Category: Fukuzawa A]]
-[[Category: Fukuzawa, A]]
+[[Category: Gautel M]]
-[[Category: Gautel, M]]
+[[Category: Pernigo S]]
-[[Category: Pernigo, S]]
+[[Category: Steiner RA]]
-[[Category: Steiner, R A]]
-[[Category: Calmodulin-binding]]
-[[Category: Cardiomyopathy]]
-[[Category: Immunoglobulin domain]]
-[[Category: Limb-girdle muscular dystrophy]]
-[[Category: Nucleotide-binding]]
-[[Category: Sarcomere]]
-[[Category: Serine/threonine-protein kinase]]
-[[Category: Tpr repeat]]
-[[Category: Transferase]]
-[[Category: Transferase-structural protein complex]]