2jp3: Difference between revisions

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-[[Image:2jp3.jpg|left|200px]]
-<!--
+==Solution Structure of the human FXYD4 (CHIF) protein in SDS micelles==
-The line below this paragraph, containing "STRUCTURE_2jp3", creates the "Structure Box" on the page.
+<StructureSection load='2jp3' size='340' side='right'caption='[[2jp3]]' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2jp3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JP3 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jp3 OCA], [https://pdbe.org/2jp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jp3 RCSB], [https://www.ebi.ac.uk/pdbsum/2jp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jp3 ProSAT]</span></td></tr>
-{{STRUCTURE_2jp3|  PDB=2jp3  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/FXYD4_RAT FXYD4_RAT] Induces a potassium channel when expressed in Xenopus oocytes.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jp/2jp3_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jp3 ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The anisotropic spin interactions measured for membrane proteins in weakly oriented micelles and in oriented lipid bilayers provide independent and potentially complementary high-resolution restraints for structure determination. Here we show that the membrane protein CHIF adopts a similar structure in lipid micelles and bilayers, allowing the restraints from micelle and bilayer samples to be combined in a complementary fashion to enhance the structural information. Back-calculation and assignment of the NMR spectrum of CHIF in oriented lipid bilayers, from the structure determined in micelles, provides additional restraints for structure determination as well as the global orientation of the protein in the membrane. The combined use of solution and solid-state NMR restraints also affords cross-validation for the structural analysis.
-'''Solution Structure of the human FXYD4 (CHIF) protein in SDS micelles'''
+Structural similarity of a membrane protein in micelles and membranes.,Franzin CM, Teriete P, Marassi FM J Am Chem Soc. 2007 Jul 4;129(26):8078-9. doi: 10.1021/ja0728371. Epub 2007 Jun , 13. PMID:17567018<ref>PMID:17567018</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-==About this Structure==
+</div>
-JP3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JP3 OCA].
+<div class="pdbe-citations 2jp3" style="background-color:#fffaf0;"></div>
+== References ==
-==Reference==
+<references/>
-Structural similarity of a membrane protein in micelles and membranes., Franzin CM, Teriete P, Marassi FM, J Am Chem Soc. 2007 Jul 4;129(26):8078-9. Epub 2007 Jun 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17567018 17567018]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Rattus norvegicus]]
-[[Category: Single protein]]
+[[Category: Franzin CM]]
-[[Category: Franzin, C M.]]
+[[Category: Marassi FM]]
-[[Category: Marassi, F M.]]
+[[Category: Teriete P]]
-[[Category: Teriete, P.]]
-[[Category: Protein]]
-[[Category: Transcription]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 09:08:24 2008''