2jmj: Difference between revisions
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==NMR solution structure of the PHD domain from the yeast YNG1 protein in complex with H3(1-9)K4me3 peptide== | ==NMR solution structure of the PHD domain from the yeast YNG1 protein in complex with H3(1-9)K4me3 peptide== | ||
<StructureSection load='2jmj' size='340' side='right' caption='[[2jmj | <StructureSection load='2jmj' size='340' side='right'caption='[[2jmj]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2jmj]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2jmj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JMJ FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jmj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jmj OCA], [https://pdbe.org/2jmj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jmj RCSB], [https://www.ebi.ac.uk/pdbsum/2jmj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jmj ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/YNG1_YEAST YNG1_YEAST] Histone-binding component of the NuA3 histone acetyltransferase complex, that acetylates Lys-14 of histone H3. Recruitment of NuA3 to nucleosomes requires methylated histone H3. In conjunction with the FACT complex, NuA3 may be involved in transcriptional regulation. YNG1 is required for the HAT activity of NuA3 but not for its integrity. Mediates the interaction of SAS3 with nucleosomes.<ref>PMID:12077334</ref> <ref>PMID:17157260</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Aitchison | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Allis | [[Category: Saccharomyces cerevisiae S288C]] | ||
[[Category: Baker | [[Category: Aitchison JD]] | ||
[[Category: Blair | [[Category: Allis CD]] | ||
[[Category: Boyle | [[Category: Baker L]] | ||
[[Category: Chait | [[Category: Blair LP]] | ||
[[Category: Ilin | [[Category: Boyle J]] | ||
[[Category: Lavender | [[Category: Chait BT]] | ||
[[Category: Li | [[Category: Ilin S]] | ||
[[Category: Patel | [[Category: Lavender H]] | ||
[[Category: Rogers | [[Category: Li H]] | ||
[[Category: Tackett | [[Category: Patel DJ]] | ||
[[Category: Tanny | [[Category: Rogers RS]] | ||
[[Category: Taverna | [[Category: Tackett AJ]] | ||
[[Category: Tanny JC]] | |||
[[Category: Taverna SD]] | |||