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{{STRUCTURE_2epp|  PDB=2epp  |  SCENE=  }}
===Solution structure of the first C2H2 type zinc finger domain of Zinc finger protein 278===


==About this Structure==
==Solution structure of the first C2H2 type zinc finger domain of Zinc finger protein 278==
[[2epp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EPP OCA].  
<StructureSection load='2epp' size='340' side='right'caption='[[2epp]]' scene=''>
 
== Structural highlights ==
==See Also==
<table><tr><td colspan='2'>[[2epp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EPP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EPP FirstGlance]. <br>
*[[Zinc Fingers|Zinc Fingers]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2epp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2epp OCA], [https://pdbe.org/2epp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2epp RCSB], [https://www.ebi.ac.uk/pdbsum/2epp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2epp ProSAT], [https://www.topsan.org/Proteins/RSGI/2epp TOPSAN]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/PATZ1_HUMAN PATZ1_HUMAN] Note=A chromosomal aberration involving PATZ1 is associated with small round cell sarcoma. Translocation t(1;22)(p36.1;q12) with EWSR1.
== Function ==
[https://www.uniprot.org/uniprot/PATZ1_HUMAN PATZ1_HUMAN] Transcriptional repressor.<ref>PMID:10713105</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Inoue, M.]]
[[Category: Large Structures]]
[[Category: Kigawa, T.]]
[[Category: Inoue M]]
[[Category: Muto, Y.]]
[[Category: Kigawa T]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Muto Y]]
[[Category: Shirouzu, M.]]
[[Category: Shirouzu M]]
[[Category: Suzuki, S.]]
[[Category: Suzuki S]]
[[Category: Tanabe, W.]]
[[Category: Tanabe W]]
[[Category: Terada, T.]]
[[Category: Terada T]]
[[Category: Yokoyama, S.]]
[[Category: Yokoyama S]]
[[Category: C2h2]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
[[Category: Transcription]]
[[Category: Zinc finger domain]]

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