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==Solution structure of the 6th C2H2 zinc finger of human Zinc finger protein 406==
==Solution structure of the 6th C2H2 zinc finger of human Zinc finger protein 406==
<StructureSection load='2elv' size='340' side='right' caption='[[2elv]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2elv' size='340' side='right'caption='[[2elv]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2elv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ELV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ELV FirstGlance]. <br>
<table><tr><td colspan='2'>[[2elv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ELV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ELV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZFAT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2elv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2elv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2elv RCSB], [http://www.ebi.ac.uk/pdbsum/2elv PDBsum], [http://www.topsan.org/Proteins/RSGI/2elv TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2elv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2elv OCA], [https://pdbe.org/2elv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2elv RCSB], [https://www.ebi.ac.uk/pdbsum/2elv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2elv ProSAT], [https://www.topsan.org/Proteins/RSGI/2elv TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ZFAT_HUMAN ZFAT_HUMAN] May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Harada, T]]
[[Category: Large Structures]]
[[Category: Kigawa, T]]
[[Category: Harada T]]
[[Category: Koshiba, S]]
[[Category: Kigawa T]]
[[Category: Structural genomic]]
[[Category: Koshiba S]]
[[Category: Tanaka, A]]
[[Category: Tanaka A]]
[[Category: Tochio, N]]
[[Category: Tochio N]]
[[Category: Tomizawa, T]]
[[Category: Tomizawa T]]
[[Category: Umehara, T]]
[[Category: Umehara T]]
[[Category: Watanabe, S]]
[[Category: Watanabe S]]
[[Category: Yokoyama, S]]
[[Category: Yokoyama S]]
[[Category: Yoneyama, M]]
[[Category: Yoneyama M]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rsgi]]
[[Category: Transcription]]
[[Category: Zfat zinc finger 1]]

Latest revision as of 19:35, 13 December 2023

Solution structure of the 6th C2H2 zinc finger of human Zinc finger protein 406Solution structure of the 6th C2H2 zinc finger of human Zinc finger protein 406

Structural highlights

2elv is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

ZFAT_HUMAN May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity).

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