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==Solution structure of the 5th C2H2 zinc finger of human Zinc finger protein 406== | ==Solution structure of the 5th C2H2 zinc finger of human Zinc finger protein 406== | ||
<StructureSection load='2elu' size='340' side='right' caption='[[2elu | <StructureSection load='2elu' size='340' side='right'caption='[[2elu]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2elu]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2elu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ELU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ELU FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2elu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2elu OCA], [https://pdbe.org/2elu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2elu RCSB], [https://www.ebi.ac.uk/pdbsum/2elu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2elu ProSAT], [https://www.topsan.org/Proteins/RSGI/2elu TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ZFAT_HUMAN ZFAT_HUMAN] May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Harada T]] | ||
[[Category: | [[Category: Kigawa T]] | ||
[[Category: | [[Category: Koshiba S]] | ||
[[Category: Tanaka | [[Category: Tanaka A]] | ||
[[Category: Tochio | [[Category: Tochio N]] | ||
[[Category: Umehara | [[Category: Umehara T]] | ||
[[Category: Watanabe | [[Category: Watanabe S]] | ||
[[Category: Yokoyama | [[Category: Yokoyama S]] | ||
[[Category: Yoneyama | [[Category: Yoneyama M]] | ||
Latest revision as of 19:35, 13 December 2023
Solution structure of the 5th C2H2 zinc finger of human Zinc finger protein 406Solution structure of the 5th C2H2 zinc finger of human Zinc finger protein 406
Structural highlights
FunctionZFAT_HUMAN May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity). |
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