2wj0: Difference between revisions

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 ==Crystal structures of Holliday junction resolvases from Archaeoglobus fulgidus bound to DNA substrate==
-<StructureSection load='2wj0' size='340' side='right' caption='[[2wj0]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
+<StructureSection load='2wj0' size='340' side='right'caption='[[2wj0]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2wj0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcfl Arcfl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WJ0 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2wj0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WJ0 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wcz|2wcz]], [[2wcw|2wcw]], [[2wiw|2wiw]], [[2wiz|2wiz]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wj0 OCA], [http://pdbe.org/2wj0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wj0 RCSB], [http://www.ebi.ac.uk/pdbsum/2wj0 PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wj0 OCA], [https://pdbe.org/2wj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wj0 RCSB], [https://www.ebi.ac.uk/pdbsum/2wj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wj0 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/HJC_ARCFU HJC_ARCFU] A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.[HAMAP-Rule:MF_01490]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wj/2wj0_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wj/2wj0_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wj0 ConSurf].
 <div style="clear:both"></div>
 ==See Also==
-*[[Resolvase|Resolvase]]
+*[[Resolvase 3D structures|Resolvase 3D structures]]
 __TOC__
 </StructureSection>
-[[Category: Arcfl]]
+[[Category: Archaeoglobus fulgidus]]
-[[Category: Basquin, J]]
+[[Category: Large Structures]]
-[[Category: Carolis, C]]
+[[Category: Synthetic construct]]
-[[Category: Koehler, C]]
+[[Category: Basquin J]]
-[[Category: Sauter, C]]
+[[Category: Carolis C]]
-[[Category: Suck, D]]
+[[Category: Koehler C]]
-[[Category: Toeroe, I]]
+[[Category: Sauter C]]
-[[Category: Dna binding protein]]
+[[Category: Suck D]]
-[[Category: Holliday junction resolvase]]
+[[Category: Toeroe I]]
-[[Category: Hydrolase]]
-[[Category: Hydrolase dna complex]]
-[[Category: Hydrolase-dna complex]]
-[[Category: Type ii restriction endonuclease]]