2wj0: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:2wj0.png|left|200px]]
-{{STRUCTURE_2wj0|  PDB=2wj0  |  SCENE=  }}
+==Crystal structures of Holliday junction resolvases from Archaeoglobus fulgidus bound to DNA substrate==
+<StructureSection load='2wj0' size='340' side='right'caption='[[2wj0]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
-===CRYSTAL STRUCTURES OF HOLLIDAY JUNCTION RESOLVASES FROM ARCHAEOGLOBUS FULGIDUS BOUND TO DNA SUBSTRATE===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2wj0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WJ0 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
-[[2wj0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJ0 OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wj0 OCA], [https://pdbe.org/2wj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wj0 RCSB], [https://www.ebi.ac.uk/pdbsum/2wj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wj0 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/HJC_ARCFU HJC_ARCFU] A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.[HAMAP-Rule:MF_01490]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wj/2wj0_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wj0 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Resolvase|Resolvase]]
+*[[Resolvase 3D structures|Resolvase 3D structures]]
+__TOC__
+</StructureSection>
 [[Category: Archaeoglobus fulgidus]]
-[[Category: Basquin, J.]]
+[[Category: Large Structures]]
-[[Category: Carolis, C.]]
+[[Category: Synthetic construct]]
-[[Category: Koehler, C.]]
+[[Category: Basquin J]]
-[[Category: Sauter, C.]]
+[[Category: Carolis C]]
-[[Category: Suck, D.]]
+[[Category: Koehler C]]
-[[Category: Toeroe, I.]]
+[[Category: Sauter C]]
-[[Category: Dna binding protein]]
+[[Category: Suck D]]
-[[Category: Holliday junction resolvase]]
+[[Category: Toeroe I]]
-[[Category: Hydrolase]]
-[[Category: Hydrolase dna complex]]
-[[Category: Hydrolase-dna complex]]
-[[Category: Type ii restriction endonuclease]]