2wef: Difference between revisions

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 ==Human 3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1) in complex with AMP, PO4 and Magnesium==
-<StructureSection load='2wef' size='340' side='right' caption='[[2wef]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+<StructureSection load='2wef' size='340' side='right'caption='[[2wef]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2wef]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WEF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WEF FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2wef]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WEF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WEF FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3'(2'),5'-bisphosphate_nucleotidase 3'(2'),5'-bisphosphate nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.7 3.1.3.7] </span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wef OCA], [http://pdbe.org/2wef PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wef RCSB], [http://www.ebi.ac.uk/pdbsum/2wef PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wef ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wef OCA], [https://pdbe.org/2wef PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wef RCSB], [https://www.ebi.ac.uk/pdbsum/2wef PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wef ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/BPNT1_HUMAN BPNT1_HUMAN] Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Has 1000-fold lower activity towards inositol 1,4-bisphosphate (Ins(1,4)P2) and inositol 1,3,4-trisphosphate (Ins(1,3,4)P3), but does not hydrolyze Ins(1)P, Ins(3,4)P2, Ins(1,3,4,5)P4 or InsP6.<ref>PMID:10224133</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
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 </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wef ConSurf].
 <div style="clear:both"></div>
+== References ==
+<references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Arrowsmith, C H]]
+[[Category: Large Structures]]
-[[Category: Berg, S Van Der]]
+[[Category: Arrowsmith CH]]
-[[Category: Berglund, H]]
+[[Category: Berglund H]]
-[[Category: Bountra, C]]
+[[Category: Bountra C]]
-[[Category: Collins, R]]
+[[Category: Collins R]]
-[[Category: Dahlgren, L G]]
+[[Category: Dahlgren LG]]
-[[Category: Edwards, A M]]
+[[Category: Edwards AM]]
-[[Category: Flodin, S]]
+[[Category: Flodin S]]
-[[Category: Flores, A]]
+[[Category: Flores A]]
-[[Category: Graslund, S]]
+[[Category: Graslund S]]
-[[Category: Hammarstrom, M]]
+[[Category: Hammarstrom M]]
-[[Category: Johansson, A]]
+[[Category: Johansson A]]
-[[Category: Johansson, I]]
+[[Category: Johansson I]]
-[[Category: Karlberg, T]]
+[[Category: Karlberg T]]
-[[Category: Kotenyova, T]]
+[[Category: Kotenyova T]]
-[[Category: Moche, M]]
+[[Category: Moche M]]
-[[Category: Nilsson, M E]]
+[[Category: Nilsson ME]]
-[[Category: Nordlund, P]]
+[[Category: Nordlund P]]
-[[Category: Nyman, T]]
+[[Category: Nyman T]]
-[[Category: Persson, C]]
+[[Category: Persson C]]
-[[Category: Structural genomic]]
+[[Category: Sagemark J]]
-[[Category: Sagemark, J]]
+[[Category: Schueler H]]
-[[Category: Schueler, H]]
+[[Category: Schutz P]]
-[[Category: Schutz, P]]
+[[Category: Siponen MI]]
-[[Category: Siponen, M I]]
+[[Category: Thorsell AG]]
-[[Category: Thorsell, A G]]
+[[Category: Tresaugues L]]
-[[Category: Tresaugues, L]]
+[[Category: Van Der Berg S]]
-[[Category: Weigelt, J]]
+[[Category: Weigelt J]]
-[[Category: Welin, M]]
+[[Category: Welin M]]
-[[Category: Wisniewska, M]]
+[[Category: Wisniewska M]]
-[[Category: Hydrolase]]
-[[Category: Sgc]]
-[[Category: Sulfur metabolism]]