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==Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS.==
==Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS.==
<StructureSection load='2w5t' size='340' side='right' caption='[[2w5t]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='2w5t' size='340' side='right'caption='[[2w5t]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2w5t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W5T FirstGlance]. <br>
<table><tr><td colspan='2'>[[2w5t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W5T FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GP9:(2R)-2,3-DIHYDROXYPROPYL+PHOSPHATE'>GP9</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2w5q|2w5q]], [[2w5r|2w5r]], [[2w5s|2w5s]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GP9:(2R)-2,3-DIHYDROXYPROPYL+PHOSPHATE'>GP9</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5t OCA], [http://pdbe.org/2w5t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w5t RCSB], [http://www.ebi.ac.uk/pdbsum/2w5t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w5t ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5t OCA], [https://pdbe.org/2w5t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w5t RCSB], [https://www.ebi.ac.uk/pdbsum/2w5t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w5t ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LTAS_STAAW LTAS_STAAW]] Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate. Is required for staphylococcal growth and cell division process (By similarity).  
[https://www.uniprot.org/uniprot/LTAS_STAAW LTAS_STAAW] Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate. Is required for staphylococcal growth and cell division process (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Freemont, P S]]
[[Category: Large Structures]]
[[Category: Grundling, A]]
[[Category: Staphylococcus aureus]]
[[Category: Lu, D]]
[[Category: Freemont PS]]
[[Category: Schneewind, O]]
[[Category: Grundling A]]
[[Category: Wormann, M E]]
[[Category: Lu D]]
[[Category: Zhang, X]]
[[Category: Schneewind O]]
[[Category: Cell membrane]]
[[Category: Wormann ME]]
[[Category: Cell wall biogenesis/degradation]]
[[Category: Zhang X]]
[[Category: Glycerol-phosphate]]
[[Category: Lta]]
[[Category: Membrane]]
[[Category: Secreted]]
[[Category: Transferase]]
[[Category: Transmembrane]]

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