2w4m: Difference between revisions

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<StructureSection load='2w4m' size='340' side='right'caption='[[2w4m]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='2w4m' size='340' side='right'caption='[[2w4m]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2w4m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W4M FirstGlance]. <br>
<table><tr><td colspan='2'>[[2w4m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W4M FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/N-acylneuraminate-9-phosphatase N-acylneuraminate-9-phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.29 3.1.3.29] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w4m OCA], [https://pdbe.org/2w4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w4m RCSB], [https://www.ebi.ac.uk/pdbsum/2w4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w4m ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w4m OCA], [https://pdbe.org/2w4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w4m RCSB], [https://www.ebi.ac.uk/pdbsum/2w4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w4m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NANP_HUMAN NANP_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: N-acylneuraminate-9-phosphatase]]
[[Category: Arrowsmith CH]]
[[Category: Arrowsmith, C H]]
[[Category: Bountra C]]
[[Category: Bountra, C]]
[[Category: Cocking R]]
[[Category: Cocking, R]]
[[Category: Edwards A]]
[[Category: Delft, F von]]
[[Category: Muniz JRC]]
[[Category: Edwards, A]]
[[Category: Oppermann U]]
[[Category: Muniz, J R.C]]
[[Category: Pike ACW]]
[[Category: Oppermann, U]]
[[Category: Roos A]]
[[Category: Pike, A C.W]]
[[Category: Ugochukwu E]]
[[Category: Roos, A]]
[[Category: Weigelt J]]
[[Category: Ugochukwu, E]]
[[Category: Yue WW]]
[[Category: Weigelt, J]]
[[Category: Von Delft F]]
[[Category: Yue, W W]]
[[Category: Carbohydrate metabolism]]
[[Category: Hdhd4]]
[[Category: Hydrolase]]
[[Category: Magnesium]]
[[Category: N-acetylneuraminate]]
[[Category: N-acetylneuraminic acid phosphatase]]
[[Category: Nanp]]
[[Category: Neu5ac-9- phosphate]]
[[Category: Sialic acid]]

Latest revision as of 18:43, 13 December 2023

The Crystal Structure of human N-acetylneuraminic acid phosphatase, NANPThe Crystal Structure of human N-acetylneuraminic acid phosphatase, NANP

Structural highlights

2w4m is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.6Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NANP_HUMAN

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2w4m, resolution 2.60Å

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