2w3x: Difference between revisions

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==CRYSTAL STRUCTURE OF A BIFUNCTIONAL HOTDOG FOLD THIOESTERASE IN ENEDIYNE BIOSYNTHESIS, CALE7==
 
<StructureSection load='2w3x' size='340' side='right' caption='[[2w3x]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
==Crystal structure of a bifunctional hotdog fold thioesterase in enediyne biosynthesis, CalE7==
<StructureSection load='2w3x' size='340' side='right'caption='[[2w3x]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2w3x]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Micromonospora_echinospora Micromonospora echinospora]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W3X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W3X FirstGlance]. <br>
<table><tr><td colspan='2'>[[2w3x]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Micromonospora_echinospora Micromonospora echinospora]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W3X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W3X FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=JEF:O-(O-(2-AMINOPROPYL)-O-(2-METHOXYETHYL)POLYPROPYLENE+GLYCOL+500)'>JEF</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w3x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w3x RCSB], [http://www.ebi.ac.uk/pdbsum/2w3x PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=JEF:O-(O-(2-AMINOPROPYL)-O-(2-METHOXYETHYL)POLYPROPYLENE+GLYCOL+500)'>JEF</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
<table>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w3x OCA], [https://pdbe.org/2w3x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w3x RCSB], [https://www.ebi.ac.uk/pdbsum/2w3x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w3x ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8KNG2_MICEC Q8KNG2_MICEC]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w3/2w3x_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w3/2w3x_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w3x ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2w3x" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Micromonospora echinospora]]
[[Category: Micromonospora echinospora]]
[[Category: Cheung, P.]]
[[Category: Cheung P]]
[[Category: Goh, L P.]]
[[Category: Goh LP]]
[[Category: Ho, Q S.]]
[[Category: Ho QS]]
[[Category: Kong, R.]]
[[Category: Kong R]]
[[Category: Kotaka, M.]]
[[Category: Kotaka M]]
[[Category: Lescar, J.]]
[[Category: Lescar J]]
[[Category: Liang, Z X.]]
[[Category: Liang ZX]]
[[Category: Liew, C W.]]
[[Category: Liew CW]]
[[Category: Mu, Y.]]
[[Category: Mu Y]]
[[Category: Qureshi, I.]]
[[Category: Qureshi I]]
[[Category: Sun, H.]]
[[Category: Sun H]]
[[Category: Enediyne biosynthesis]]
[[Category: Hotdog fold]]
[[Category: Hydrolase]]
[[Category: Thioesterase]]

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OCA