2vvx: Difference between revisions

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 <StructureSection load='2vvx' size='340' side='right'caption='[[2vvx]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2vvx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VVX FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2vvx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VVX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VVX FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vvw|2vvw]], [[2vvy|2vvy]], [[2i39|2i39]], [[2uxe|2uxe]], [[2jbx|2jbx]], [[2jby|2jby]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.746&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vvx OCA], [http://pdbe.org/2vvx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vvx RCSB], [http://www.ebi.ac.uk/pdbsum/2vvx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vvx ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vvx OCA], [https://pdbe.org/2vvx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vvx RCSB], [https://www.ebi.ac.uk/pdbsum/2vvx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vvx ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/A52_VACCW A52_VACCW] Bcl-2-like protein which targets host toll-like receptor signaling complexes to suppress innate immune response. Interacts with host TRAF6 to activate p38 and subsequently induce the expression of several cytokines such as IL-10. Associates also with host IRAK2 to inhibit NF-kappa-B signaling.<ref>PMID:12566418</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
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 [[Category: Large Structures]]
 [[Category: Vaccinia virus]]
-[[Category: Abrescia, N G.A]]
+[[Category: Abrescia NGA]]
-[[Category: Alderton, D]]
+[[Category: Alderton D]]
-[[Category: Bahar, M W]]
+[[Category: Bahar MW]]
-[[Category: Chen, R A.J]]
+[[Category: Chen RA-J]]
-[[Category: Cooray, S]]
+[[Category: Cooray S]]
-[[Category: Graham, S C]]
+[[Category: Graham SC]]
-[[Category: Grimes, J M]]
+[[Category: Grimes JM]]
-[[Category: Owens, R J]]
+[[Category: Owens RJ]]
-[[Category: Smith, G L]]
+[[Category: Smith GL]]
-[[Category: Stuart, D I]]
+[[Category: Stuart DI]]
-[[Category: Whalen, D M]]
+[[Category: Whalen DM]]
-[[Category: Bcl-2 family]]
-[[Category: Host-virus interaction]]
-[[Category: Immunomodulator]]
-[[Category: Irak2]]
-[[Category: Nf-kb activation]]
-[[Category: Traf6]]
-[[Category: Viral protein]]