2vph: Difference between revisions

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[[Image:2vph.png|left|200px]]


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==Crystal structure of the human protein tyrosine phosphatase, non- receptor type 4, PDZ domain==
The line below this paragraph, containing "STRUCTURE_2vph", creates the "Structure Box" on the page.
<StructureSection load='2vph' size='340' side='right'caption='[[2vph]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2vph]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VPH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VPH FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vph OCA], [https://pdbe.org/2vph PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vph RCSB], [https://www.ebi.ac.uk/pdbsum/2vph PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vph ProSAT]</span></td></tr>
{{STRUCTURE_2vph| PDB=2vph |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/PTN4_HUMAN PTN4_HUMAN] May act at junctions between the membrane and the cytoskeleton.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vp/2vph_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vph ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 4, PDZ DOMAIN===
==See Also==
 
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2VPH is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VPH OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith CH]]
[[Category: Bountra, C.]]
[[Category: Bountra C]]
[[Category: Burgess-Brown, N.]]
[[Category: Burgess-Brown N]]
[[Category: Delft, F Von.]]
[[Category: Edwards A]]
[[Category: Edwards, A.]]
[[Category: Elkins JM]]
[[Category: Elkins, J M.]]
[[Category: Filippakopoulos P]]
[[Category: Filippakopoulos, P.]]
[[Category: Kavanagh K]]
[[Category: Kavanagh, K.]]
[[Category: Knapp S]]
[[Category: Knapp, S.]]
[[Category: Pike ACW]]
[[Category: Pike, A C.W.]]
[[Category: Roos AK]]
[[Category: Roos, A K.]]
[[Category: Wang J]]
[[Category: Wang, J.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Von Delft F]]
[[Category: Cytoplasm]]
[[Category: Cytoskeleton]]
[[Category: Dephosphorylation]]
[[Category: Hydrolase]]
[[Category: Megakaryocyte]]
[[Category: Protein phosphatase]]
[[Category: Ptpmeg]]
[[Category: Ptpn4]]
[[Category: Structural protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:04:44 2009''

Latest revision as of 18:27, 13 December 2023

Crystal structure of the human protein tyrosine phosphatase, non- receptor type 4, PDZ domainCrystal structure of the human protein tyrosine phosphatase, non- receptor type 4, PDZ domain

Structural highlights

2vph is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PTN4_HUMAN May act at junctions between the membrane and the cytoskeleton.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2vph, resolution 1.90Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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