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==Crystal structure of F96S mutant of Plasmodium falciparum triosephosphate isomerase with 3- phosphoglycerate bound at the dimer interface==
==Crystal structure of F96S mutant of Plasmodium falciparum triosephosphate isomerase with 3- phosphoglycerate bound at the dimer interface==
<StructureSection load='2vfe' size='340' side='right' caption='[[2vfe]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2vfe' size='340' side='right'caption='[[2vfe]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vfe]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VFE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VFE FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vfe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VFE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VFE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3PG:3-PHOSPHOGLYCERIC+ACID'>3PG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lzo|1lzo]], [[1m7p|1m7p]], [[1woa|1woa]], [[1wob|1wob]], [[1lyx|1lyx]], [[1m7o|1m7o]], [[1o5x|1o5x]], [[1vga|1vga]], [[1ydv|1ydv]], [[2vfd|2vfd]], [[2vff|2vff]], [[2vfg|2vfg]], [[2vfh|2vfh]], [[2vfi|2vfi]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PG:3-PHOSPHOGLYCERIC+ACID'>3PG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vfe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vfe OCA], [https://pdbe.org/2vfe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vfe RCSB], [https://www.ebi.ac.uk/pdbsum/2vfe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vfe ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vfe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vfe OCA], [http://pdbe.org/2vfe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vfe RCSB], [http://www.ebi.ac.uk/pdbsum/2vfe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vfe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TPIS_PLAFA TPIS_PLAFA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Triose Phosphate Isomerase|Triose Phosphate Isomerase]]
*[[Triose phosphate isomerase 3D structures|Triose phosphate isomerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Plafa]]
[[Category: Large Structures]]
[[Category: Triose-phosphate isomerase]]
[[Category: Balaram, H]]
[[Category: Balaram, P]]
[[Category: Banerjee, M]]
[[Category: Gayathri, P]]
[[Category: Murthy, M R.N]]
[[Category: Vijayalakshmi, A]]
[[Category: 3-phosphoglycerate]]
[[Category: Dimer interface]]
[[Category: Fatty acid biosynthesis]]
[[Category: Gluconeogenesis]]
[[Category: Glycolysis]]
[[Category: Isomerase]]
[[Category: Lipid synthesis]]
[[Category: Pentose shunt]]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
[[Category: Triosephosphate isomerase]]
[[Category: Balaram H]]
[[Category: Balaram P]]
[[Category: Banerjee M]]
[[Category: Gayathri P]]
[[Category: Murthy MRN]]
[[Category: Vijayalakshmi A]]

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