2vc7: Difference between revisions

No edit summary
No edit summary
 
(One intermediate revision by the same user not shown)
Line 3: Line 3:
<StructureSection load='2vc7' size='340' side='right'caption='[[2vc7]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='2vc7' size='340' side='right'caption='[[2vc7]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vc7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VC7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VC7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vc7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VC7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VC7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HT5:(4S)-4-(DECANOYLAMINO)-5-HYDROXY-3,4-DIHYDRO-2H-THIOPHENIUM'>HT5</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HT5:(4S)-4-(DECANOYLAMINO)-5-HYDROXY-3,4-DIHYDRO-2H-THIOPHENIUM'>HT5</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vc5|2vc5]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vc7 OCA], [https://pdbe.org/2vc7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vc7 RCSB], [https://www.ebi.ac.uk/pdbsum/2vc7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vc7 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aryldialkylphosphatase Aryldialkylphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.8.1 3.1.8.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vc7 OCA], [http://pdbe.org/2vc7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vc7 RCSB], [http://www.ebi.ac.uk/pdbsum/2vc7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vc7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PHP_SULSO PHP_SULSO]] Has a low paraoxonase activity. Also active, but with a lower activity, against other oregano-phosphorus insecticides such as Dursban, Coumaphos, pNP-butanoate or parathion.<ref>PMID:15909078</ref>
[https://www.uniprot.org/uniprot/PHP_SACS2 PHP_SACS2] Has a low paraoxonase activity. Also active, but with a lower activity, against other organo-phosphorus insecticides such as Dursban, Coumaphos, pNP-butanoate or parathion.<ref>PMID:15909078</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 35: Line 33:
*[[Phosphotriesterase 3D structures|Phosphotriesterase 3D structures]]
*[[Phosphotriesterase 3D structures|Phosphotriesterase 3D structures]]
*[[Serum Paraoxonase|Serum Paraoxonase]]
*[[Serum Paraoxonase|Serum Paraoxonase]]
*[[SsoPox: a natural lactonase with promiscuous phosphotriesterase activities|SsoPox: a natural lactonase with promiscuous phosphotriesterase activities]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aryldialkylphosphatase]]
[[Category: Atcc 35091]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Chabriere, E]]
[[Category: Saccharolobus solfataricus]]
[[Category: Dupuy, J]]
[[Category: Chabriere E]]
[[Category: Elias, M]]
[[Category: Dupuy J]]
[[Category: Lecomte, C]]
[[Category: Elias M]]
[[Category: Manco, G]]
[[Category: Lecomte C]]
[[Category: Mandrich, L]]
[[Category: Manco G]]
[[Category: Masson, P]]
[[Category: Mandrich L]]
[[Category: Merone, L]]
[[Category: Masson P]]
[[Category: Moniot, S]]
[[Category: Merone L]]
[[Category: Rochu, D]]
[[Category: Moniot S]]
[[Category: Rossi, M]]
[[Category: Rochu D]]
[[Category: Biotechnology]]
[[Category: Rossi M]]
[[Category: Enzyme evolution]]
[[Category: Hydrolase]]
[[Category: Hyperthermophilic]]
[[Category: Lactonase]]
[[Category: Phosphotriesterase]]
[[Category: Promiscuous activity]]
[[Category: Quorum sensing]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA