2v9p: Difference between revisions
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==Crystal structure of papillomavirus E1 hexameric helicase DNA-free form== | ==Crystal structure of papillomavirus E1 hexameric helicase DNA-free form== | ||
<StructureSection load='2v9p' size='340' side='right' caption='[[2v9p]], [[Resolution|resolution]] 3.00Å' scene=''> | <StructureSection load='2v9p' size='340' side='right'caption='[[2v9p]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2v9p]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9P OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[2v9p]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Deltapapillomavirus_4 Deltapapillomavirus 4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V9P FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v9p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9p OCA], [https://pdbe.org/2v9p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v9p RCSB], [https://www.ebi.ac.uk/pdbsum/2v9p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v9p ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/VE1_BPV1 VE1_BPV1] ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Helicase|Helicase]] | *[[Helicase 3D structures|Helicase 3D structures]] | ||
*[[Replication protein E1|Replication protein E1]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Deltapapillomavirus 4]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Antson AA]] | ||
[[Category: | [[Category: Isupov MN]] | ||
[[Category: | [[Category: Kovalevskiy OV]] | ||
[[Category: | [[Category: Lebedev AA]] | ||
[[Category: | [[Category: Sanders CM]] | ||
[[Category: | [[Category: Sizov D]] | ||