2ji5: Difference between revisions

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[[Image:2ji5.png|left|200px]]


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==Structure of UMP kinase from Pyrococcus furiosus complexed with UTP==
The line below this paragraph, containing "STRUCTURE_2ji5", creates the "Structure Box" on the page.
<StructureSection load='2ji5' size='340' side='right'caption='[[2ji5]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2ji5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JI5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JI5 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr>
{{STRUCTURE_2ji5| PDB=2ji5 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ji5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ji5 OCA], [https://pdbe.org/2ji5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ji5 RCSB], [https://www.ebi.ac.uk/pdbsum/2ji5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ji5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PYRH_PYRFU PYRH_PYRFU] Catalyzes the reversible phosphorylation of UMP to UDP, with ATP as the most efficient phosphate donor.<ref>PMID:15698963</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ji/2ji5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ji5 ConSurf].
<div style="clear:both"></div>


===STRUCTURE OF UMP KINASE FROM PYROCOCCUS FURIOSUS COMPLEXED WITH UTP===
==See Also==
 
*[[Uridylate kinase|Uridylate kinase]]
 
== References ==
==About this Structure==
<references/>
2JI5 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JI5 OCA].
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
[[Category: Marco-Marin, C.]]
[[Category: Marco-Marin C]]
[[Category: Rubio, V.]]
[[Category: Rubio V]]
[[Category: Allosteric regulation]]
[[Category: Amino acid kinase]]
[[Category: Kinase]]
[[Category: Phosphotranspherase]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Pyrimidine metabolism]]
[[Category: Transferase]]
[[Category: Ump kinase]]
[[Category: Uridylate kinase]]
 
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