2jeb: Difference between revisions

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-==STRUCTURE OF A 9-SUBUNIT ARCHAEAL EXOSOME BOUND TO MN IONS==
-<StructureSection load='2jeb' size='340' side='right' caption='[[2jeb]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+==Structure of a 9-subunit archaeal exosome bound to Mn ions==
+<StructureSection load='2jeb' size='340' side='right'caption='[[2jeb]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2jeb]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JEB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JEB FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2jeb]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JEB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JEB FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2br2|2br2]], [[2c37|2c37]], [[2c38|2c38]], [[2c39|2c39]], [[2je6|2je6]], [[2jea|2jea]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jeb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jeb OCA], [http://pdbe.org/2jeb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jeb RCSB], [http://www.ebi.ac.uk/pdbsum/2jeb PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jeb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jeb OCA], [https://pdbe.org/2jeb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jeb RCSB], [https://www.ebi.ac.uk/pdbsum/2jeb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jeb ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/ECR1_SULSO ECR1_SULSO]] Probably involved in degradation of a variety of RNA species; could act a RNA-binding component of the exosome (Potential). [[http://www.uniprot.org/uniprot/ECX1_SULSO ECX1_SULSO]] Probably involved in the 3'->5' degradation of a variety of RNA species (Potential).
+[https://www.uniprot.org/uniprot/RRP42_SACS2 RRP42_SACS2] Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.[HAMAP-Rule:MF_00622]<ref>PMID:15951817</ref> <ref>PMID:20488184</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/2jeb_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/2jeb_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
@@ Line 30: / Line 31: @@
 ==See Also==
-*[[Exonuclease|Exonuclease]]
+*[[Exosome 3D structures|Exosome 3D structures]]
-*[[Exosome|Exosome]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Atcc 35091]]
+[[Category: Large Structures]]
-[[Category: Conti, E]]
+[[Category: Saccharolobus solfataricus]]
-[[Category: Lorentzen, E]]
+[[Category: Conti E]]
-[[Category: Archaeal]]
+[[Category: Lorentzen E]]
-[[Category: Exonuclease]]
-[[Category: Exoribonuclease]]
-[[Category: Exosome]]
-[[Category: Hydrolase]]
-[[Category: Nuclease]]
-[[Category: Phosphorolytic]]
-[[Category: Rna]]
-[[Category: Rna degradation]]
-[[Category: Rna-binding]]
-[[Category: Rnase ph]]
-[[Category: Rrp4]]
-[[Category: Rrp41]]
-[[Category: Rrp42]]