2j5i: Difference between revisions
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<StructureSection load='2j5i' size='340' side='right' caption='[[2j5i]], [[Resolution|resolution]] 1.80Å' scene=''> | ==Crystal Structure of Hydroxycinnamoyl-CoA Hydratase-Lyase== | ||
<StructureSection load='2j5i' size='340' side='right'caption='[[2j5i]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2j5i]] is a 12 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2j5i]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_fluorescens Pseudomonas fluorescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J5I FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5i OCA], [https://pdbe.org/2j5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j5i RCSB], [https://www.ebi.ac.uk/pdbsum/2j5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j5i ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/HCHL_PSEFL HCHL_PSEFL] Catalyzes the hydration of the acyl-CoA thioester of ferulic acid and the subsequent retro-aldol cleavage of the hydrated intermediate to yield vanillin (4-hydroxy-3-methoxy-benzaldehyde).<ref>PMID:9461612</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j5/2j5i_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j5/2j5i_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Pseudomonas fluorescens]] | ||
[[Category: Brzozowski | [[Category: Brzozowski AM]] | ||
[[Category: Grogan | [[Category: Grogan G]] | ||
[[Category: Lebedev | [[Category: Lebedev A]] | ||
[[Category: Leonard | [[Category: Leonard PM]] | ||
[[Category: Marshall | [[Category: Marshall CM]] | ||
[[Category: Smith | [[Category: Smith DJ]] | ||
[[Category: Verma | [[Category: Verma CS]] | ||
[[Category: Walton | [[Category: Walton NJ]] | ||