2iy4: Difference between revisions

<StructureSection load='2iy4' size='340' side='right'caption='[[2iy4]], [[Resolution|resolution]] 2.31&Aring;' scene=''>

<table><tr><td colspan='2'>[[2iy4]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IY4 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.31&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iy4 OCA], [https://pdbe.org/2iy4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iy4 RCSB], [https://www.ebi.ac.uk/pdbsum/2iy4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iy4 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/DPS_LISMO DPS_LISMO] Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Does not bind to DNA (By similarity). Dps is important for full resistance to heat and cold shocks and is essential for full virulence of this bacterium. It seems to play a direct or indirect role on the production and/or stability of listeriolysin O.<ref>PMID:12383509</ref> <ref>PMID:15758237</ref> <ref>PMID:16098690</ref>  

*[[Ferritin 3D structures|Ferritin 3D structures]]

[[Category: Large Structures]]

[[Category: Listeria monocytogenes]]

[[Category: Bellapadrona G]]

[[Category: Chiancone E]]

[[Category: Ilari A]]

[[Category: Stefanini S]]