2iwd: Difference between revisions

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==Oxacilloyl-acylated MecR1 extracellular antibiotic-sensor domain.==
==Oxacilloyl-acylated MecR1 extracellular antibiotic-sensor domain.==
<StructureSection load='2iwd' size='340' side='right' caption='[[2iwd]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='2iwd' size='340' side='right'caption='[[2iwd]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2iwd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IWD FirstGlance]. <br>
<table><tr><td colspan='2'>[[2iwd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IWD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1S6:(2R,4S)-5,5-DIMETHYL-2-[(1R)-1-{[(5-METHYL-3-PHENYL-1,2-OXAZOL-4-YL)CARBONYL]AMINO}-2-OXOETHYL]-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>1S6</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2iwb|2iwb]], [[2iwc|2iwc]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1S6:(2R,4S)-5,5-DIMETHYL-2-[(1R)-1-{[(5-METHYL-3-PHENYL-1,2-OXAZOL-4-YL)CARBONYL]AMINO}-2-OXOETHYL]-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>1S6</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwd OCA], [http://pdbe.org/2iwd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iwd RCSB], [http://www.ebi.ac.uk/pdbsum/2iwd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2iwd ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwd OCA], [https://pdbe.org/2iwd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iwd RCSB], [https://www.ebi.ac.uk/pdbsum/2iwd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iwd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MECR_STAAN MECR_STAAN]] Penicillin-interactive protein and potential antirepressor (By similarity).  
[https://www.uniprot.org/uniprot/MECR_STAAN MECR_STAAN] Penicillin-interactive protein and potential antirepressor (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Garcia-Castellanos, R]]
[[Category: Large Structures]]
[[Category: Gomis-Ruth, F X]]
[[Category: Staphylococcus aureus]]
[[Category: Guevara, T]]
[[Category: Garcia-Castellanos R]]
[[Category: Mallorqui-Fernandez, G]]
[[Category: Gomis-Ruth FX]]
[[Category: Marrero, A]]
[[Category: Guevara T]]
[[Category: Antibiotic resistance]]
[[Category: Mallorqui-Fernandez G]]
[[Category: Bacterial antibiotic resistance]]
[[Category: Marrero A]]
[[Category: Beta-lactamase]]
[[Category: Beta-lactamic antibiotic]]
[[Category: Methicillin resistance]]
[[Category: Mrsa]]
[[Category: Oxacillin]]
[[Category: Penicillin-binding protein]]

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