2iu7: Difference between revisions
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==Site directed mutagenesis of key residues involved in the catalytic mechanism of Cyanase== | |||
<StructureSection load='2iu7' size='340' side='right'caption='[[2iu7]], [[Resolution|resolution]] 1.91Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2iu7]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IU7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IU7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.91Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iu7 OCA], [https://pdbe.org/2iu7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iu7 RCSB], [https://www.ebi.ac.uk/pdbsum/2iu7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iu7 ProSAT]</span></td></tr> | |||
</table> | |||
=== | == Function == | ||
[https://www.uniprot.org/uniprot/CYNS_ECOLI CYNS_ECOLI] Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | |||
== Evolutionary Conservation == | |||
== | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | |||
[[ | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iu/2iu7_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iu7 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Anderson PM]] | ||
[[Category: | [[Category: Guilloton M]] | ||
[[Category: | [[Category: Joachimiak A]] | ||
[[Category: | [[Category: Walsh MA]] | ||
Latest revision as of 17:25, 13 December 2023
Site directed mutagenesis of key residues involved in the catalytic mechanism of CyanaseSite directed mutagenesis of key residues involved in the catalytic mechanism of Cyanase
Structural highlights
FunctionCYNS_ECOLI Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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