2co0: Difference between revisions

No edit summary
No edit summary
 
(7 intermediate revisions by the same user not shown)
Line 1: Line 1:
==WDR5 AND UNMODIFIED HISTONE H3 COMPLEX AT 2.25 ANGSTROM==
 
<StructureSection load='2co0' size='340' side='right' caption='[[2co0]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
==WDR5 and unmodified Histone H3 complex at 2.25 angstrom==
<StructureSection load='2co0' size='340' side='right'caption='[[2co0]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2co0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CO0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2co0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CO0 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cnx|2cnx]], [[2gnq|2gnq]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2co0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2co0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2co0 RCSB], [http://www.ebi.ac.uk/pdbsum/2co0 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2co0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2co0 OCA], [https://pdbe.org/2co0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2co0 RCSB], [https://www.ebi.ac.uk/pdbsum/2co0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2co0 ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/H31_HUMAN H31_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/co/2co0_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/co/2co0_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2co0 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 24: Line 27:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2co0" style="background-color:#fffaf0;"></div>
==See Also==
*[[WD-repeat protein 3D structures|WD-repeat protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 29: Line 36:
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Allis, C D.]]
[[Category: Large Structures]]
[[Category: Graybosch, D M.]]
[[Category: Allis CD]]
[[Category: Li, H.]]
[[Category: Graybosch DM]]
[[Category: Patel, D J.]]
[[Category: Li H]]
[[Category: Ruthenburg, A J.]]
[[Category: Patel DJ]]
[[Category: Verdine, G L.]]
[[Category: Ruthenburg AJ]]
[[Category: Wang, W.]]
[[Category: Verdine GL]]
[[Category: Histone presenter]]
[[Category: Wang W]]
[[Category: Hox gene activation]]
[[Category: Leukemia]]
[[Category: Lysine methylation]]
[[Category: Mll1]]
[[Category: Transcription]]
[[Category: Transcription activation]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA