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[[Image:2c8h.gif|left|200px]]<br />
<applet load="2c8h" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2c8h, resolution 1.65&Aring;" />
'''STRUCTURE OF THE PN LOOP Q182A MUTANT C3BOT1 EXOENZYME (NAD-BOUND STATE, CRYSTAL FORM I)'''<br />


==About this Structure==
==Structure of the PN loop Q182A mutant C3bot1 Exoenzyme (NAD-bound state, crystal form I)==
2C8H is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum] with SO4 and NAD as [http://en.wikipedia.org/wiki/ligands ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2C8H OCA].  
<StructureSection load='2c8h' size='340' side='right'caption='[[2c8h]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2c8h]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C8H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C8H FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c8h OCA], [https://pdbe.org/2c8h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c8h RCSB], [https://www.ebi.ac.uk/pdbsum/2c8h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c8h ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q7M0L1_CLOBO Q7M0L1_CLOBO]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c8/2c8h_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c8h ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Exoenzyme 3D structures|Exoenzyme 3D structures]]
__TOC__
</StructureSection>
[[Category: Clostridium botulinum]]
[[Category: Clostridium botulinum]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Boquet, P.]]
[[Category: Boquet P]]
[[Category: Flatau, G.]]
[[Category: Flatau G]]
[[Category: Menetrey, J.]]
[[Category: Menetrey J]]
[[Category: Menez, A.]]
[[Category: Menez A]]
[[Category: Stura, E.A.]]
[[Category: Stura EA]]
[[Category: NAD]]
[[Category: SO4]]
[[Category: adp-ribosyltransferase]]
[[Category: artt motif]]
[[Category: bacterial toxins]]
[[Category: c3 exoenzyme]]
[[Category: glycosyltransferase]]
[[Category: nad]]
[[Category: pn loop]]
[[Category: transferase]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov  5 15:25:52 2007''

Latest revision as of 17:09, 13 December 2023

Structure of the PN loop Q182A mutant C3bot1 Exoenzyme (NAD-bound state, crystal form I)Structure of the PN loop Q182A mutant C3bot1 Exoenzyme (NAD-bound state, crystal form I)

Structural highlights

2c8h is a 4 chain structure with sequence from Clostridium botulinum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.65Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q7M0L1_CLOBO

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2c8h, resolution 1.65Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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